Strengthen that LES to Protect Against GERD! Updated 2025!

 

Our lower esophageal sphincter (LES) is a sphincter that connects the top of our stomach (cardia) with the bottom of our esophagus. Our LES first relaxes when we swallow to allow food to enter our stomach. Our LES then closes tightly after the food enters our stomach to keep stomach acid and pepsin from traveling up our esophagus, causing inflammation. Our LES can also relax, allowing air to travel out of our stomach as a burp. Our LES also naturally relaxes to allow vomiting. Our LES must maintain proper muscle tone and pressure to work effectively. Too little pressure and weak muscle tone may cause reflux if increased intra-abdominal pressure or a reduction in gravity is present. For example, what happens if you have a weak LES and lie down to sleep after eating a large meal? Gravity is no longer putting pressure on our lower esophageal sphincter to help keep it closed, and the increased intra-abdominal pressure from lying down and having a full stomach may cause nighttime reflux. However, if our LES muscle tone is too tight and fails to relax, it may cause achalasia. When achalasia occurs, food can become stuck within our esophagus after swallowing, causing regurgitation and chest pain. Maintaining proper LES tone and pressure is essential for proper digestive health.1

 

Our Lower Esophageal Sphincter May Become Weakened Over a Period of Time From:

 

If your LES is weakened, excess intra-abdominal pressure can easily push gastric contents into your esophagus, causing reflux. In addition, if the LES is weakened, reflux can easily occur during sleep because of the lack of LES pressure that typically holds gastric contents within our stomach.10 Sleeping on your left side at night is more anatomically correct. Sleeping on your left side can increase LES pressure, causing it to remain closed and help relieve nighttime reflux. Strengthening the LES is hard because few exercises can straighten our sphincter (research states that breathing exercises may help). You can, however, physically take excess pressure off the LES and stomach by wearing loose clothing and losing excess weight, which helps it regain muscle tone. Eating less food at meals can also help. You can also limit foods that weaken the LES, treat SIBO, and attempt to switch to medications that do not undermine the functioning of your LES. Supplements may help strengthen your LES, lower gastric pressure, and repair nerve damage. All of these suggestions should help your LES function better.

 

Improve the Health of Your LES Protocol

 

    • Chew your food very well before swallowing, and eat smaller portions. The less your gastrointestinal system has to work digesting your food, the better your overall digestion.
    • Sleep on your left side at night.
    • Avoid nicotine, caffeine, and alcohol.
    • Avoid ingesting chocolate and mint.
    • NOW calcium citrate powder – take five hundred milligrams, twice daily, mixed well with water.
    • GeroNova R-Plus lipoic acid – take one softgel when you wake up and one between lunch and dinner. Do not take if you have mercury amalgams in your mouth or are mercury-burdened.
    • Digest Gold – take two with every meal.
    • Pure Encapsulations – Peptic-Care ZC – one capsule with a meal, twice daily.
    • Supplement with DGL.
    • Ensure proper stomach acid production. Try ingesting organic apple cider vinegar by adding it to some of your meals (mix nicely) to provide the short-chain fatty acid acetate, which may help relieve upper gut dysbiosis and improve LES muscle tone. Betaine HCL ingestion with meals might also help.
    • Test for a vitamin B6 deficiency (Spectracell), and if you have one, supplement with the lowest dose possible (test your vitamin B6 levels every few months to see if they have been restored) daily to avoid vitamin B6-induced neuropathy.
    • Test for vitamin B12 deficiency (serum B12 and methylmalonic acid levels) and see if you need to supplement.
    • Do not wear tight clothing or tight belts. They put too much pressure on the LES, eventually weakening it.
    • Lose excess weight if possible.

If all else fails to relieve LES problems, try supplemental melatonin:

      • Life Extension melatonin – take one to five milligrams before bed; do not take such a large dose for longer than two weeks. You might even need to increase to as high as fifty milligrams for a few days to see if you find relief. If you require long-term melatonin supplementation, reduce to one milligram or less nightly, which might be safer and hopefully not cause any adverse hormonal fluctuations seen with larger doses. It is always best to try to maximize endogenous melatonin production.

Calcium citrate could strengthen your LES when it comes into direct contact with it. This can happen when you drink the calcium mixed with water in a powder. One of calcium’s roles in the body is to be used as a muscle toner, causing contractions. Calcium citrate strengthening the LES is just a theory; no in vivo studies have been done. 11

R-lipoic acid has multiple benefits within our body, but in this role, it improves the health of our vagus nerve, which communicates with our LES, telling it to relax or tighten.12

Digestive enzymes help break down the food we ingest in our stomachs, reducing bloating and excess pressure on our LES.

Melatonin has been shown to increase LES tone and pressure. Melatonin is a hormone produced while we sleep and a potent antioxidant that can lower inflammation and promote healing. Also, melatonin reduces stomach acid and gastrin production while we sleep.13 14 15 16 17

 

Restore Your Digestive Enzyme Production!

 

Take one capsule of Enzymedica Digest Gold at the start of a meal (twice daily) to help with digestion and food assimilation if you have infrequent indigestion. Digest Gold contains an optimal blend of different digestive and systemic enzymes and a blend of different amylases, proteases, cellulases, and lipases. Enzymedica has added ATPro to its enzyme, a blend of supplements and magnesium that can help stimulate pepsin and gastric acid production by increasing ATP production. Enzymedica has found a way to help our body naturally increase stomach acid without using betaine HCL or pepsin directly. I do not recommend that people with mercury amalgams or mercury-burdened supplements use Digest Gold because of the ALA (alpha lipoic acid) in ATPro. If you are suffering from mercury burden or have mercury amalgams, I cannot recommend Digest Gold because the ALA might improperly mobilize mercury. Instead, I recommend you use Gutzyme. Adenosine triphosphate is a form of energy that our mitochondria produce within our cells, which is also essential in regulating our migrating motor complex.

Digestive enzymes should not be taken indefinitely unless needed (an example of when required would be if you have a poorly functioning pancreas or liver, or have had a cholecystectomy). A better suggestion would be to train your body to produce more digestive enzymes and ensure optimal liver/gallbladder/pancreas function. You can train your body to make greater amounts of digestive enzymes and help your organs function better by using Swedish bitters.

 

Swedish bitters (gentian)

 

Swedish bitters are a mixture of different herbs, depending on the brand. Your average Swedish bitter tonic can help stimulate digestion and even help your body make natural digestive enzymes. Swedish bitter herbs also help maintain proper gallbladder function and gastric emptying.

Gentian is a bitter herb from a plant native to China and is used in most digestive bitter formulas. It has been shown to help ease gallbladder issues and indigestion. Gentian helps increase appetite, stimulates the production of digestive juices, increases pancreatic activity, and boosts blood supply to our digestive organs. It is also known to facilitate the bile flow. If you have an ulcer, do not use Gentian; it can irritate it!

Of the three digestive enzymes recommended, I recommend Urban Moonshine Citrus because of the addition of D-limonene. Do not use any digestive bitter supplement that contains alcohol if you have severe gastritis or an ulcer. Urban Moonshine offers a digestive bitter supplement that uses apple cider vinegar instead of alcohol, which you may be able to tolerate if you have gastritis or an ulcer.